Statistical Analysis of Medical Studies
Some Biostatistics or What does the „true” mean in a medical study?
Overview
Experimental situation
1. Contingency table
Contingency-table
To analyse new diagnostic methods statistically
Notions
Accuracy
Specificity
Sensitivity
2. Chi-square test (2*2 tables)
?2 test – example
?2 test – cautions, limitations
3. Cohen's Kappa (2*2 tables)
Cohen's Kappa – example
Cohen's Kappa – values
4. Cost matrices
5. ROC-Analysis
ROC analysis – example
Gold standard
Definition:
Many methods of the quantitative analysis
PPT Slide
Quantitative Studies
Normal Data
Normal Brain SPECT
Where from?
Validation
Validity
Applications, Examples
Heart Study
1. NM Study of Myocardial Perfusion
Study Result
Polar Images of SPECT study
3.A way to generate normal data
Statistics of the generation method
Email: ssip@inf.u-szeged.hu
Home Page: http://www.inf.u-szeged.hu/~ssip