Elastic Registration of Multimodal Prostate Images |
![Icon of project](./img/ProstateFuse/prostatefusion_icon_120x120[1].png) |
- Members: Zoltan Kato
- Funded by:
- Hungarian Scientific Research Fund (OTKA) - CNK80370,
- National Innovation Office (NIH),
- TAMOP-4.2.1/B-09/1/KONV-2010-0005 program of the Hungarian National Development Agency
- Partners:
- Robert Marti (Computer Vision and Robotics Group, Universitat de Girona, Spain),
- Arnau Oliver (Computer Vision and Robotics Group, Universitat de Girona, Spain),
- Xavier Llado (Computer Vision and Robotics Group, Universitat de Girona, Spain),
- Desire Sidibe (Le2i, UMR CNRS, Le Creusot, France),
- Fabrice Meriaudeau (Le2i, UMR CNRS, Le Creusot, France),
- Soumya Ghose (Le2i, UMR CNRS, Le Creusot, France),
- Jhimli Mitra (Le2i, UMR CNRS, Le Creusot, France)
- Lifetime: 2011 Jan - 2012 Jan
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DescriptionA novel method is developed for non-rigid registration of transrectal ultrasound and magnetic resonance prostate images based on a non-linear regularized framework of point correspondences obtained from a statistical measure of shape-contexts. The segmented prostate shapes are represented by shape-contexts and the Bhattacharyya distance between the shape contexts is used to find the point correspondences between the 2D fixed and moving images. The registration method involves parametric estimation of the non-linear diffeomorphism between the multimodal images and has its basis in solving a set of non-linear equations of thin-plate splines. The solution is obtained from the minimization of image difference between the fixed and the transformed image, where the latter is represented by a set of non-linear thin-plate spline equations defined over the moving image. Image difference minimization leads to the maximum overlap of the fixed and the transformed moving images but, the gray-level transformation of the moving image does not produce clinically acceptable transformations of the anatomical targets. Therefore, the regularized bending energy of the thin-plate splines along with the localization error of established correspondences is jointly minimized with the fixed and transformed image difference. The registration accuracies of the proposed method are evaluated in 20 pairs of prostate mid-gland ultrasound and magnetic resonance images. The results obtained in terms of Dice similarity coefficient show an average of 0.980 ± 0.004, average 95% Hausdorff distance of 1.63 ± 0.48 mm and mean target registration and target localization errors of 1.60 ± 1.17 mm and 0.15 ± 0.12 mm respectively.
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Publications to cite:- Jhimli Mitra, Zoltan Kato, Robert Marti, Arnau Oliver, Xavier Llado, Soumya Ghose, Joan C. Vilanova, Fabrice Meriaudeau, A Non-linear Diffeomorphic Framework for Prostate Multimodal Registration, In Proceedings of International Conference on Digital Image Computing: Techniques and Applications, IEEE, Noosa, Queensland, Australia, pp. 31-36, 2011.
[bibtex]
- Jhimli Mitra, Zoltan Kato, Robert Marti, Arnau Oliver, Xavier Llado, Desire Sidibe, Soumya Ghose, Joan C. Vilanova, Josep Comet, Fabrice Meriaudeau, A spline-based non-linear diffeomorphism for multimodal prostate registration, In Medical Image Analysis, vol. 16, no. 6, pp. 1259-1279, 2012.
[bibtex]
- Jhimli Mitra, Zoltan Kato, Soumya Ghose, Desire Sidibe, Robert Martí, Xavier Llado, Arnau Oliver, Joan C. Vilanova, Fabrice Meriaudeau, Spectral clustering to model deformations for fast multimodal prostate registration, In Proceedings of International Conference on Pattern Recognition, IEEE, Tsukuba Science City, Japan, pp. 2622-2625, 2012.
[bibtex]
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